https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27712 Wed 11 Apr 2018 12:01:24 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27718 via the enzyme, cytochrome P450, family 2, subfamily E, polypeptide 1 (CYP2E1). Acrylamide was administered to male CD1 mice for three or sixmonths at a dose of 0.18 mg/kg bodyweight/day. DNA damage was detected in germ cells and maturespermatozoa of exposed mice without compromising their overall fertility. The use of resveratrol, anantioxidant and known CYP2E1 inhibitor, was found to ameliorate the DNA damage in both germ cells andspermatozoa. However, extended resveratrol treatment (six months, 10.0 mg/kg bw/week) resulted inpremature activation of these cells. Thus the DNA damage found in spermatozoa after chronic acrylamideadministration can be alleviated but an alternative CYP2E1 inhibitor may be required.]]> Sat 24 Mar 2018 07:24:39 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27719 Sat 24 Mar 2018 07:24:39 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:40281 Fri 29 Jul 2022 13:23:12 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16821 Fri 16 Aug 2024 06:33:41 AEST ]]>